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From a clinical and applied standpoint, this supports the notion of moving toward cycle-aware, but not rigidly “cycle-synced,” strategies: for most healthy, well-nourished women, modest phase-dependent adaptations—such as ensuring adequate energy and micronutrient intake in the mid-luteal phase, or considering the timing of high-intensity exercise relative to phases associated with lower subjective well-being—are likely to be sufficient, whereas in conditions such as PCOS, obesity, diabetes or functional hypothalamic amenorrhea, a more deliberate alignment of nutrition and training with endocrine and inflammatory profiles may help stabilize glycemic control, ovulatory function, and symptom burden [95,172]