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Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis - PMC
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Compared with conventional 2D cell cultures, 3D organoids or spheroids, either scaffold-based or scaffold-free, better recapitulate the in vivo microenvironment, enhance biological relevance, and enable mechanistic investigations of drug responses in a tissue-mimetic context
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